Articles By Renjith kumar

Suppose you have an exciting new drug which is potentially capable of alleviating much suffering. Suppose also that it is a solid and it doesn’t dissolve in water. In fact it will only dissolve in hydrocarbons. How do you ensure that when orally taken, the drug will get into the bloodstream (water) and travel to the point of action? Salt selection is your answer.

Developing a new pharmaceutical active ingredient isn’t just about developing a molecule with the best biological activity. The physical form has to be optimised to ensure the top possible performance and that no one can find a superior form and usurp your hard won patent position.